Browsing Department of Biotechnology by Subject "Nanotechnology"
Now showing items 1-15 of 15
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Antimicrobial, anticancer and catalytic activities of green synthesized Avocado seed extract-gold nanoparticles
(University of the Western Cape, 2019)Nature through billions of years of trial and error has produced an immeasurable amount of natural systems like plants, birds and animals. The intelligence of nature is hidden in these natural systems and researchers are ... -
Biogenic synthesis of gold nanoparticles using red and green pear fruit extracts
(University of the Western Cape, 2019)There has been a growing interest in the design of biocompatible and environmentally affable nanoparticles (NPs) among scientists to develop novel and safe biomaterials for use in various biomedical applications. This can ... -
Development of a receptor targeted nanotherapy using a proapoptotic peptide
(University of the Western Cape, 2015)The prevalence of obesity amongst South Africans is alarming, with more than 29% of men and 56% of women considered to be obese. Angiogenesis, a process for development of new blood vessels play a major role in growth and ... -
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ... -
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ... -
Development of nanotechnology-based therapeutic approaches to treat HIV
(University of the Western Cape, 2012)The rapidly expanding field of nanotechnology has been the focus of many biologists with regard to drug delivery. The ability of nanoparticles to enter cellular compartments makes it possible to explore specific treatment ... -
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
(2013)The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ... -
Evaluation of the anticancer and molecular effects of green synthesized silver nanoparticles
(University of the Western Cape, 2023)Globally, cancer is considered the second leading cause of death with a staggering tally of 10 million deaths. Breast, lung, colon, rectum and prostate cancers are amongst the most commonly diagnosed cancers. The current ... -
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects
(University of the Western Cape, 2020)Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ... -
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
(University of the Western Cape, 2023)The incidence and prevalence of obesity and its related diseases has nearly tripled and is increasing at an alarming rate worldwide. Several modern methods for the management and treatment of obesity are available, with ... -
Novel gold nanoparticles of drought tolerance enabler GYY4137
(University of the Western Cape, 2019)Different nanoparticles have the ability to improve plant tolerance to drought stress. In the study we report for the first time novel morpholin-4-ium 4-methoxyphenyl (morpholino) phosphinodithioate capped- gold nanoparticles ... -
Peptide functionalised gold nanorods for the selective eradication of target cells using photothermal therapy
(University of the Western Cape, 2019)Cancer is one of the leading causes of death, worldwide. Mortality tolls are estimated to reach approximately 13.1 million in 2030. These statistics suggest that current therapeutic strategies are not effective. This is ... -
Synthesis of silver doped titanium dioxide nanocomposites using tea extract from Aspalathus linearis and evaluation of their antibacterial effects.
(University of the Western Cape, 2018)Despite the wide success of antimicrobial agents against waterborne pathogens, waterborne disease continues to pose a threat to both mankind and animals. A major concern is that certain bacteria have developed resistance ... -
Synthesis of silver nanoparticles and investigating their antimicrobial effects
(University of the Western Cape, 2015)Water is essential for life, yet access to safe drinking water is still a major concern worldwide due to waterborne diseases. The current study proposes silver nanoparticles (AgNPs) as an antibacterial agent. Silver ... -
Zirconium-induced physiological and biochemical responses in two genotypes of Brassica napus L.
(University of the Western Cape, 2015)South Africa is one of two countries responsible for the production of approximately 80% of the world’s Zr. The increase in mining activity has detrimental effects on the environment, especially crop plants, as more ...