Browsing Department of Biotechnology by Subject "Pharmacogenomics"
Now showing items 1-3 of 3
-
Genomic diversity and functional analysis of the solute carrier genes within indigenous African and Cape Admixed populations
(University of the Western Cape, 2016)Solute carrier transporters belonging to the major facilitator family of membrane transporter are increasingly being recognized as a possible mechanism to explain inter-individual variation in drug efficacy and response. ... -
Inter-individual genetic variation and the development of hypertension in a Xhosa African population of Eastern Cape, South Africa
(University of the Western Cape, 2022)Cardiovascular diseases (CVD) are the leading cause of death globally, accounting for 18.6 million deaths. Hypertension (HTN) drives the global burden of CVD and is a leading cause of cardiovascular-related mortality with ... -
Prevalence of uncontrolled hypertension and the pharmacogenomics of enalapril-induced adverse effects among patients in the Vhembe district
(University of the Western Cape, 2022)Controlling blood pressure (BP) among individuals with hypertension is important in the prevention of cardiovascular diseases (CVDs). However, maintaining optimal BP levels in individuals who are prone to drug-induced ...