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Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
(University of the Western Cape, 2004)
Human angiotensin-converting enzyme (ACE) is a key enzyme in the
regulation of blood pressure via the renin-angiotensin and kallikrein-kinin
systems. A number of orally active drugs have been developed over the
years ...