Department of Biotechnology: Recent submissions
Now showing items 121-140 of 368
-
Peptide functionalised gold nanorods for the selective eradication of target cells using photothermal therapy
(University of the Western Cape, 2019)Cancer is one of the leading causes of death, worldwide. Mortality tolls are estimated to reach approximately 13.1 million in 2030. These statistics suggest that current therapeutic strategies are not effective. This is ... -
Involvement of abscisic acid and H2O2 in antioxidant enzyme activities mediated by nitric oxide synthase-like activity in maize
(University of the Western Cape, 2018)In recent years, nitric oxide (NO) has emerged as an important endogenous plant signalling molecule that mediates many developmental and physiological processes. NO regulates the activity of antioxidant enzymes in response ... -
Comparative molecular, physiological and proteomic analyses of maize and sorghum subjected to water deficit stress
(University of the Western Cape, 2019)Drought is a major abiotic stress which causes not only differences between the mean yield and the potential yield but also yield variation from year to year. Although selection for genotypes with improved productivity ... -
3,3'-diindolylmethane improves drought tolerance of Zea mays through enhancing antioxidant activity
(University of the Western Cape, 2018)Maize is one of the most abundantly produced cereals and contributes to about 40% of the global cereal production. This figure will have to increase in order to feed the ever-growing human population. One of the major ... -
Differences in visual attention processing: An event-related potential comparative analysis within psychotic disorders
(University of the Western Cape, 2018)Introduction: Sustained attention is known to be dysfunctional in psychotic disorders. Sustained attention is the ability to remain focused on a specific time-locked stimulus within a task. We aimed to determine whether ... -
The in vitro detection and measurement of the unfolded protein response in Saccharomyces cerevisiae
(University of the Western Cape, 2018)Bioethanol is currently the most widely used biofuel and can be used as a direct replacement for current fossil fuel based transportation fuels. Consolidated bioprocessing (CBP), in which bioethanol is produced in a single ... -
Investigation of the role of AtNOGC1, a guanylyl cyclase protein in response to abiotic and biotic stress
(University of the Western Cape, 2018)Agricultural production is one of the most important sectors which provide food for the growing world population which is estimated to reach 9.7 billion by 2050, thus there is a need to produce more food. Climate change, ... -
Validation and application of a highly discriminating and rapid 10-locus Y-STR DNA profiling system
(University of the Western Cape, 2019)DNA profiling the male specific region on the Y-chromosome is fundamental to forensic practise. Its recognised as a powerful analytical tool for investigation of sexual assault when the DNA evidence is highly admixed. ... -
Differences in visual attention processing: An event-related potential comparative analysis within psychotic disorders
(University of the Western Cape, 2019)INTRODUCTION: Sustained attention is known to be dysfunctional in psychotic disorders. Sustained attention is the ability to remain focused on a specific time-locked stimulus within a task. We aimed to determine whether ... -
A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting
(University of the Western Cape, 2018)The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that ... -
Exploring anti-tyrosinase bioactive compounds from the Cape flora
(University of the Western Cape, 2018)Tyrosinase is an enzyme widely distributed in the biosphere and is found in many species of bacteria, fungi, animals, and plants; it is associated with melanin production. Even though it possesses many beneficial properties ... -
A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting
(University of the Western Cape, 2018)The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that ... -
Exploring anti-tyrosinase bioactive compounds from the Cape flora
(University of the Western Cape, 2018)Tyrosinase is an enzyme widely distributed in the biosphere and is found in many species of bacteria, fungi, animals, and plants; it is associated with melanin production. Even though it possesses many beneficial properties ... -
Molecular analysis of red colouration in 'Bon Rouge' pear (Pyrus communis L.)
(University of the Western Cape, 2018)The 'Bon Rouge' pear cultivar was developed from a bud mutation on a 'Bon Chretien' pear tree. The latter is characterised by green fruit skin and leaves, while 'Bon Rouge' is characterised by red leaves and red fruit skin ... -
Comparison of plasmids from clinical Lactobacillus strains
(University of the Western Cape, 2018)The vaginal mucosa is dominated by Gram positive, rod shaped lactobacilli which serve as a natural barrier against infection. In both healthy and BV infected women Lactobacillus crispatus and Lactobacillus jensennii has ... -
Recombinant expression of cytochrome P450-2D6 and its application in tamoxifen metabolism
(University of the Western Cape, 2018)Breast cancer is regarded as the most common form of cancer in women and it comprises of approximately 23 % of female cancers, while affecting women at any age range. For oestrogen receptor positive patients, tamoxifen is ... -
Comparison of plasmids from clinical Lactobacillus strains
(University of the Western Cape, 2018)The vaginal mucosa is dominated by Gram positive, rod shaped lactobacilli which serve as a natural barrier against infection. In both healthy and BV infected women Lactobacillus crispatus and Lactobacillus jensennii has ... -
Improving Evaporation Rate of Mine Wastewater
(University of the Western Cape, 2018)The treatment of mine water at the eMalahleni Water Reclamation Plant (EWRP) results in the production of large volumes of brine. Different brine management methods have been applied to dispose the brine but the evaporation ... -
Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
(University of the Western Cape, 2017)Glycine max (soybean) is an important crop species globally as it is used as a protein-rich food and feed crop and as a source of oils used in the food and biofuel industry. However, the growth and yield of soybean is ... -
AtNOGC1 protein bioelectrode for the determination of stress signalling molecules - Nitric Oxide (NO), Carbon Monoxide (CO) and Calcium ion (Ca2+)
(University of the Western Cape, 2018)It has been estimated that the world population will reach about 10 billion by the year 2050 and in order to accommodate the increased demand of food, the world agricultural production needs to rise by 70 % in the year ...