Browsing School of Pharmacy by Subject "Molecular dynamics"
Now showing items 1-2 of 2
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Homology modelling and characterization of three-dimensional (3d) protein structures of selected variants of cyp3a4
(University of the Western Cape, 2022)The efficacy and toxicity of several drugs and prodrugs are influenced by the interindividual genetic variations in drug-metabolising enzymes. Cytochrome P450 enzymes constitute the major metabolising enzymes in humans. ... -
Structure-Based Virtual Screening of Selected Malaria Box Compounds Against a Multi-Staged Protein (Falstatin) in Plasmodium falciparum
(University of the Western Cape, 2021)Malaria disease poses substantial health risks to many nations, especially in Africa, where it primarily affects pregnant women, children, and immunocompromised patients. However, current antimalarial drugs have limitations ...