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Now showing items 101-108 of 108
Microbiological parameters that influence the treatment outcomes of monodrug and multidrug-resistant tuberculosis
(University of the Western Cape, 2017)
Previous studies have reported microbiological parameters such as HIV infection, resistance to
anti-TB drugs such as fluoroquinolones, resistance to previous treatment with anti-TB drugsand
extrapulmonary TB, causing poor ...
Antimicrobial discovery from South African marine algae
(University of the Western Cape., 2018)
Antimicrobials are chemical compounds that destroy or inhibit the growth of microorganisms.
The majority of these antimicrobials are actually natural products or natural product derived
with key examples being the pioneer ...
Active encapsulation of diclofenac sodium into liposomes for ophthalmic preparations
(University of the Western Cape, 2018)
Liposomes as a drug carrier in the pharmaceutical industry has gained currency since its
discovery in 1965 by Bangham A. D. Liposomes have been shown to improve bioavailability
as they can be delivered to target sites ...
Disposal Practices for Unwanted Medicines from Households in Johannesburg
(University of the Western Cape, 2017)
A mixed research method was used where quantitative research facilitated qualitative
research. Three questionnaires were drafted and distributed by email to respondents in the
Johannesburg area. One questionnaire was for ...
Pharmacovigilance: An Assessment of Knowledge, Attitude and Practice of Healthcare Professionals towards Adverse Drug Reactions Reporting In Central Region of Malawi
(University of the Western Cape, 2017)
AIM OF THE STUDY: To assess level of knowledge, attitude and practices of dispensing healthcare
professionals towards adverse drug reactions (ADR) reporting and to determine if there are any
differences in knowledge, ...
Adverse pregnancy outcomes among HIV-positive pregnant women treated with efavirenz-containing antiretroviral drugs: a retrospective cohort study in the Cape Flats
(University of the Western Cape, 2017)
The use of efavirenz (EFV) in the first trimester of pregnancy
remains controversial. In South Africa, the use of EFV-containing antiretroviral
therapy (ART) as part of a Fixed Dose Combination (FDC) during the first
trimester ...
Post-market assessment of the quality of first line regimen fixed-dose combination antiretrovirals in South Africa
(University of the Western Cape, 2017)
The rapid increase in access to new antiretrovirals (ARVs) worldwide and, especially in sub-Saharan Africa, coupled with the well-documented problem of poor quality ARVs in developing countries has underscored the need for ...
Tacrine, trolox and tryptoline as lead compounds for the design and synthesis of multi-target drugs for Alzheimer's disease therapy
(University of the Western Cape, 2016)
The cascade of neurotoxic events involved in the pathogenesis of Alzheimer's disease may explain the inefficacy of currently available treatment based on acetylcholinesterase inhibitors (AChEI - donepezil, galantamine, ...