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The physicochemical characterisation, compatibility testing and solid-state form screening of terizidone - Pyridoxine combinations
(University of Western Cape, 2021)
Terizidone (TZD) is considered an essential anti-tuberculosis drug and in South
Africa it is prescribed as part of the multi-drug resistant tuberculosis (MDR-TB) treatment
regimen. From a literature study it became ...
Selected antiretroviral and anti-tuberculosis drug combinations by non-covalent bonding
(University of Western Cape, 2021)
Treatment of the human immunodeficiency virus (HIV) and tuberculosis (TB) infections have become very complicated due to the advent of drug resistance. Drug combinations offer an alternative approach to reducing the emergence ...
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)
Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ...
Synthesis and characterisation of biomimetic immunostimulatory lipid-polymer hybrid nanoparticles
(University of the Western Cape, 2022)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis),
remains a fatal infectious disease and one of the top ten leading causes of mortality,
particularly in developing countries. Current drug therapy ...
Evaluation of selected polycyclic compounds as resistance modulators in Mycobacterium tuberculosis
(University of the Western Cape, 2022)
Progressive development of resistance to various chemotherapeutic agents used in the management
of infectious diseases presents a serious problem in global public health. Increasing levels of
antimicrobial resistance in ...