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Now showing items 21-30 of 32
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year pharmacy students
(University of the Western Cape, 2010)
Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ...
Spectroelectrochemical graphene-silver/zinc oxide nanoparticulate phenotype biosensors for ethambutol and pyrazinamide
(University of the Western Cape, 2019)
Tuberculosis (TB), a deadly disease second to HIV/AIDS, is a global health problem.
Diagnosis of active tuberculosis is tedious and requires expensive procedures since there is
no recognizable method for sole detection ...
Graphenated organic nanoparticles immunosensors for the detection of TB biomarkers
(University of the Western Cape, 2017)
Pulmonary Tuberculosis (TB) a disease second to HIV/AIDS is a global health problem that
arises in two states; as an active state and as a latent state. Diagnosis of active TB is tedious
and requires expensive procedures ...
Gold nanoparticulate modified thioglycolic acid (tga) phenotype nanobiosensor for tuberculosis drugs
(University of the Western Cape, 2022)
Tuberculosis (TB) carries on being a major global health issue and it is responsible for 1.5 million disease-related mortality in 2020, according to the World Health organisation (WHO). One of the major causes of death ...
The use of Dioxy MP 14 (stabilized aqueous chlorine dioxide) to control environmental airborne microorganisms
(University of the Western Cape, 2009)
Dioxy MP 14 is a locally developed form of stabilized chlorine dioxide in an aqueous medium. It has all the sanitizing properties of chlorine dioxide gas, a neutral compound of chlorine in the +IV oxidation state, which ...
Synthesis and characterization of magneto-electric nanoparticles for delivery of antituberculosis drugs across the blood-brain barrier
(University of the Western Cape, 2022)
The anatomical structure of the brain at the blood–brain barrier (BBB) creates a limitation for the
movement of drugs into the central nervous system (CNS). Although anti-infective drugs effective
against Mycobacterium ...
Synthesis and characterisation of biomimetic immunostimulatory lipid-polymer hybrid nanoparticles
(University of the Western Cape, 2022)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis),
remains a fatal infectious disease and one of the top ten leading causes of mortality,
particularly in developing countries. Current drug therapy ...
Evaluation of selected polycyclic compounds as resistance modulators in Mycobacterium tuberculosis
(University of the Western Cape, 2022)
Progressive development of resistance to various chemotherapeutic agents used in the management
of infectious diseases presents a serious problem in global public health. Increasing levels of
antimicrobial resistance in ...
Carbon dot – polythionine nanocomposite sensor for the remediation of antibiotics in water
(University of the Western Cape, 2022)
Antibiotics are a necessary part of the world today where their main purpose is to
counter bacteria and diseases. Antibiotics are used in many areas which include
apiculture, domestic, livestock and medically. Since ...
Organometallic improvement of some tuberculosis drugs
(University of the Western Cape, 2023)
Metal-based drugs are preferred motifs that serve as major pharmacophores in bioactive
compounds for a variety of diseases, including as tuberculosis (TB). Heterocyclic, Schiff bases,
aliphatic amines and other ligands ...