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An investigation into the antimicrobial and immune modulatory effects of Sutherlandia frutescens and Salvia africana-lutea extracts and their respective biogenic nanoparticles
(University of the Western Cape, 2020)
The prevalence of cancer and antibiotic-resistant microbes has led to the necessity of affordable, efficacious, non-toxic and easily accessible therapeutic approaches. There is numerous anecdotal evidence that African ...
Characterizing water quality of rivers and underlying aquifers in the Nuwejaars Catchment, South Africa
(University of Western Cape, 2020)
Non-perennial rivers are the main source of surface water in drylands. These rivers are unpredictable and highly variable in terms of flow regime and water quality. Despite their abundance, and importance in the landscape, ...
Graphol and vanadia-linkedzink-doped lithium manganese silicate nanoarchitectonic platforms for supercapatteries
(University of Western cape, 2020)
Energy storage technologies are rapidly being developed due to the increased awareness of global warming and growing reliance of society on renewable energy sources. Among various electrochemical energy storage technologies, ...
Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs
(University of Western Cape, 2020)
Tuberculosis (TB) remains a global epidemic despite the fact that treatment has been available since the 1950’s. This disease is highly contagious and spreads via transmission of the Mycobacterium Tuberculosis (MTB) tubercle ...
Developing a citizen science framework for water resources protection to facilitate operationalization of resource directed measures at catchment level, South Africa
(University of Western Cape, 2021)
Maintenance of water resources protection practice for water availability, uninterrupted water utilization, and for ecosystem integrity is critical for sustainable achievement of resource security for all. Therefore, ...
Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
(University of Western Cape, 2020)
Natural products have been an important source of drugs and novel lead compounds in drug
discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise
to medicinally relevant agents. ...
Computational analysis of multi-omic data for the elucidation of molecular mechanisms of neuroblastoma
(University of Western Cape, 2021)
Neuroblastoma is the most common extracranial solid tumor in childhood. The survival rates of patients with neuroblastoma, especially those in the high-risk category, are still low despite varied therapies. The detailed ...
Fractional Black-Scholes equations and their robust numerical simulations
(University of Western Cape, 2020)
Conventional partial differential equations under the classical Black-Scholes approach
have been extensively explored over the past few decades in solving option
pricing problems. However, the underlying Efficient Market ...
Ongoing development of guidelines for biosimilar medicines assessment in Uganda: Critical evaluation and recommendations for inclusion
(University of Western Cape, 2020)
A Biosimilar is defined as a biologic product that is similar but not identical to the reference/originator biologic product. Biologic products have raised hopes of improving the quality of life especially in the treatment ...
Novel Nanostructure Electrocatalysts for Oxygen Reduction and Hydrogen Evolution Reactions
(University of Western Cape, 2020)
widespread use of fossil energy has been most convenient to the world, while they also cause environmental pollution and global warming. Therefore, it is necessary to develop clean and renewable energy sources, among which, ...