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Now showing items 91-100 of 138
Biosimilar’s Growth in Pharmerging Markets: An Analysis of the Regulatory Environments
(University of the Western Cape, 2020)
The introduction of biosimilars to health care markets across the globe has had some success
in increasing competition and improving the cost of healthcare. While savings are important
for driving the biosimilar uptake, ...
Synthesis and evaluation of fluorescently linked polycyclic cage derivatives for application in neurodegenerative disorders
(University of the Western Cape, 2020)
Neurodegenerative diseases (ND) are chronic and progressive in nature, and
characterized by the gradual loss of neurons in various regions of the central
nervous system (CNS). ND include Alzheimer's disease (AD), Parkinson's ...
Disposal of unused medicines from households in Cape Town
(University of Western Cape, 2019)
Evidence indicates that most South African households do not dispose of unused medicines in the
manner prescribed by the medicine’s regulatory authority. This trend is not unique to South Africa,
but several developing ...
An assessment of current practice patterns of TB/HIV at primary health care clinics in the Western Cape and a needs assessment for clinic-based training among final year pharmacy students
(University of the Western Cape, 2010)
Tuberculosis and mv
Tuberculosis (TB) is a major contributor to the disease burden in developing countries
resulting in the deaths of approximately 2 million people a year. South Africa (SA) has one (
of the highest ...
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)
Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ...
Selection, synthesis and evaluation of novel drug-like compounds from a library of virtual compounds designed from natural products with antiplasmodial activities
(University of the Western Cape, 2020)
Malaria is an infectious disease which continues to kill more than one million people every year and the African continent accounts for most of the malaria death worldwide. New classes of medicine to combat malaria are ...
Isolation and Bioassay evaluation of Angiotensin Converting Enzyme inhibitory compounds of Centella asiatica
(University of the Western Cape, 2019)
Hypertension is by far the most common risk factor for cardiovascular disease (CVD), which has been identified as the leading cause of death worldwide and a major economic burden in developing countries. Over the years, ...
Change Management in a biopharmaceutical company
(University of Western Cape, 2020)
This study aimed to review the change management implemented in a Biopharmaceutical company in Cape Town in the light of existing literature on change management theory. Three main constructs were identified: process of ...
The formulation and characterisation of corticosteroid loaded Ethosomes for topical delivery
(University of the Western Cape, 2020)
Background/Introduction: Atopic dermatitis (AD) is one of the most prevalent diseases worldwide. It is a rapidly growing field of study with several research avenues to explore its pathophysiology and to find innovative ...
The impact of Niacin on PCSK9 levels in vervet monkeys (Chlorocebus aethiops)
(University of Western Cape, 2020)
Cardiovascular diseases (CVDs) such as ischaemic heart diseases, heart failure and stroke
remain a major cause of death globally. Various deep-rooted factors influence CVD
development; these include but are not limited ...