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Phytochemical and biological studies of Helichrysum cymosum
(University of the Western Cape, 2020)
Diabetes mellitus (DM) is well known as a group of systemic metabolic disorders with a considerable mortality rate around the world. Hyperglycemia is the main consequence of DM, which results from the shortage in insulin ...
Cheminformatic Approaches to Hit-Prioritization and Target Prediction of Potential Anti-MRSA Natural Products
(University of the Western Cape, 2020)
The growing resistance of Methicillin-Resistant Staphylococcus aureus (MRSA) to currently prescribed drugs has resulted in the failure of prevention and treatment of different infections caused by the superbug. Therefore, ...
Mobile phone applications targeted towards medicine adherence in Africa: A systematic review
(University of Western Cape, 2020)
According to the WHO (2017), non-communicable diseases (NCDs) which include
stroke, cancer, heart disease, chronic respiratory disease and diabetes is the leading
cause of death and is responsible for seventy one percent ...
Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
(University of Western Cape, 2020)
Natural products have been an important source of drugs and novel lead compounds in drug
discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise
to medicinally relevant agents. ...
Ongoing development of guidelines for biosimilar medicines assessment in Uganda: Critical evaluation and recommendations for inclusion
(University of Western Cape, 2020)
A Biosimilar is defined as a biologic product that is similar but not identical to the reference/originator biologic product. Biologic products have raised hopes of improving the quality of life especially in the treatment ...
Novel norbornane derivatives as potential neuroprotective agents
(University of Western Cape, 2020)
Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological
functions as a result of gradual degeneration of neurons in the central nervous system. Even
though they are classified as ...
Use and consumer perceptions of dietary supplements in the fitness community of Gaborone, Botswana
(University of Western Cape, 2020)
Health authorities around the world, including stringent ones, struggle to regulate dietary supplements. Health claims and actual effects of these products on users therefore are not adequately studied and monitored. In ...
Cheminformatic approaches to hit-prioritization and target prediction of potential anti-mrsa natural products
(University of Western Cape, 2020)
The growing resistance of Methicillin-Resistant Staphylococcus aureus (MRSA) to currently prescribed drugs has resulted in the failure of prevention and treatment of different infections caused by the superbug. Therefore, ...
The impact of Niacin on PCSK9 levels in vervet monkeys (Chlorocebus aethiops)
(University of the Western Cape, 2020)
Cardiovascular diseases (CVDs) such as ischaemic heart diseases, heart failure and stroke
remain a major cause of death globally. Various deep-rooted factors influence CVD
development; these include but are not limited ...
Change Management in a Biopharmaceutical Company
(University of the Western Cape, 2020)
This study aimed to review the change management implemented in a Biopharmaceutical company in Cape Town in the light of existing literature on change management theory. Three main constructs were identified: process of ...