Browsing Magister Pharmaceuticae - MPharm by Issue Date
Now showing items 1-20 of 89
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Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart
(University of the Western Cape, 2004)This thesis discussed the cardiovascular effects of the aqueous leaf extract and a fraction of the methanol extract of Leonotis leonurus, a plant commonly used in traditional medicine in South Africa for the treatment of ... -
The development and evaluation of the Objective Structured Dispensing Examination (OSDE) for use in an undergraduate pharmacy training programme
(University of the Western Cape, 2004) -
The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material
(University of the Western Cape, 2004)Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing ... -
Acute and chronic toxicity of the flavonoid-containing plant, Artemisia afra in rodents
(University of the Western Cape, 2005)The aim of this study was to investigate the possible toxicity of the flavonoid-containing plant, Artemisia afra and especially establish the safety of the aqueous extract of this plant after acute and chronic administration ... -
Evaluation of guidelines for clinical trials of traditional plant medicines
(University of the Western Cape, 2005)The World Health Organization estimates that 4 billion people use herbal medicine for some aspect of primary health care. These herbal products are however mostly used without the necessary clinical trial done to prove ... -
Pharmacological evaluation of some central nervous system effects of Cotyledon Orbiculata
(University of the Western Cape, 2005)The use of traditional medicine through the use of medicinal plants in Africa and especially in South Africa has long been considered an important characteristic of people's daily lives and socio-cultural heritage. Cotyledon ... -
The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia
(University of the Western Cape, 2006)Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied ... -
An investigation into the relationship between personality type, as measured by the Keirsey Bates Temperament Sorter, choice of practice setting and job satisfaction of pharmacists who graduated from the University of the Western Cape over the period 1990-2005
(University of the Western Cape, 2006)For the study the Keirsey Bates Temperament Sorter was completed by 602 pharmacy students during their study period at the University of the Western Cape. The results showed that the pharmacy students had a tendency towards ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
(University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
Development, implementation and evaluation of a diabetes educational outreach inervention for pharmacists
(University of the Western Cape, 2007)Increasing diabetes prevalence rates, poor involvement of and limited knowledge among health care professionals in disease management, and poor implementation of guidelines are barriers to quality diabetes care. This thesis ... -
Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic ... -
A comparative study of the phosphodiesterase 4 inhibitory activity of artemisia afra, Leonotis leonorus and mentha longifolia plant medicines
(University of the Western Cape, 2007)The specific objectives of this study were to investigate whether Artemisia Afra, Leonotis leonorous and Mentha Longiflora have PDE 4 inhibitory activity, to determine and compare the levels of the total phenolic compunds ... -
Determination of plasma concentrations using LC/MS and pharmacokinetics of ofloxacin in patients with multi-drug resistant tuberculosis and in patients with multi-drug resistant tuberculosis coinfected with hiv
(2009)Many studies have investigated the pharmacokinetics of anti-tuberculosis drugs in patients infected with tuberculosis. However, little is known about the pharmacokinetics of the drugs that are used in the treatment of ... -
The use of dioxy MP 14 (stabilized aqueous chlorine dioxide) to control environmental airborne microorganisms
(2009)Dioxy MP 14 is a locally developed form of stabilized chlorine dioxide in an aqueous medium. It has all the sanitizing properties of chlorine dioxide gas, a neutral compound of chlorine in the +IV oxidation state, which ... -
Design, implementation and evaluation of a model for Service-learning in Pharmacy (SLIP) at a tertiary hospital
(University of the Western Cape, 2009)In recent years the focus of pharmacy practice has changed from being primarily 'drug-centred to' one which is 'patient-centred' (El-Awady et al., 2006, p. l ). Developments in pharmacy curricula worldwide are reflecting ... -
Investigation of factors influencing pharmaceutical services and their relation to quality pharmaceutical service delivery in hospitals of a private health care provider group
(2009)Efforts to improve the quality of service delivery are an ongoing feature in different organisations. In the private health care sector, particularly pharmaceutical services in private hospitals, such efforts are important ... -
Design, implementation and evaluation of a model for service-learning in pharmacy (slip) at a Tertiary hospital
(2009)Background In recent years the focus of pharmacy practice has changed from being primarily ‘drugcentred to’ one which is ‘patient-centred’ (El-Awady et al., 2006, p.1). Developments in pharmacy curricula worldwide are ... -
Comparison of the sutherlandioside B levels in two commercially available Sutherlandia frutescence preparations and the effect of elevated temperature and humidity on these levels
(University of the Western Cape, 2009)Sutherlandia frutescens (tribe Galegeae, Fabaceae), is a popular medicinal plant traditionally used in South Africa. In 2000, a company called Phyto Nova (Pty) Ltd. initiated large-scale cultivation and contract manufacturing ... -
Evaluation of antihistamines for in vitro antimalarial activity against Plasmodium falciparum
(2010)The declining efficacy of antimalarial drugs against resistant Plasmodium falciparum strains in several endemic regions has amplified the world’s burden of neglected diseases. This has highlighted the need for alternate ...
