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Now showing items 21-30 of 43
The implementation of in vitro assays to screen environmental samples for male reproductive toxicity
(University of the Western Cape, 2010)
Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals which interfere with, or have adverse effects on the production, distribution and function of natural hormones, thereby affecting normal endocrine ...
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
(University of the Western Cape, 2017)
Over the years, microorganisms have become resistant to commonly used antimicrobial agents
leading to multidrug resistance. This is believed to occur even with new classes of therapeutic
agents thus creating a challenge ...
The assessment of Namibian water resources for endocrine disruptors
(University of the Western Cape, 2018)
Namibia is the driest sub-Saharan country in Africa and it is characterised by low
and variable rainfall. As a result, potable water in this mostly semi-arid country is
considered an extremely valuable resource. Given ...
Effects of Libyan traditional plants on the reproductive system of male and female rats
(University of the Western Cape, 2015)
In different parts of the world, medicinal plants have demonstrated a lot of health
benefits to mankind and remains an important source for the discovery of new
bio-active compounds. Libya is a typical example of a country ...
The antifungal effect of Salvadora persica and Euclea natalensis on Candida isolates from Libyan patients with type 2 Diabetes mellitus.
(University of the Western Cape, 2018)
Improved oral hygiene plays a vital role on quality of health and well-being of diabetic
patients. Poor oral health leads to an increased incidence of oral diseases, particularly
oral candidiasis. The emergence and global ...
Potential anti-melanogenic effects of selected South African plants on b16 melanoma cells
(University of the Western Cape, 2019)
Dyspigmentation is one of the commonest dermatological presenting complaints from patients, particularly hyperpigmentation. Hyperpigmentation can cause dangerous psychological and emotional impact on self-perception and ...
The effects of artificial and natural sweeteners on various physiological systems
(University of the Western Cape, 2011)
This study aimed to investigate the effects of commercially available natural (sugar cane molasses, white sugar and brown sugar) and artificial (Canderel, Equal, Natreen, Sweetex, Splenda and Swheet) sweeteners on various ...
Protein expression and antifungal effect of fluconazole-resistant Candida species following effective in vitro treatment with K21, a novel antifungal agent
(University of Western Cape, 2019)
Background: Oropharyngeal candidiasis, caused by the fungus Candida, is the most common
opportunistic infection affecting the quality of life of immunocompromised patients. Fluconazole
is widely used as the first line ...
Semen characteristics of free-ranging African elephants (Loxodonta africana) and Southern white rhinoceros (Ceratotherium simum simum) using Computer-aided sperm analysis, Electron microscopy and Genomics as diagnostic tools
(University of the Western Cape, 2016)
The survival of free-ranging (in situ) African elephant and Southern white rhinoceros populations are currently being challenged on a daily basis in Africa. Reproductive health is considered a vital component of species ...
Investigating the anti-cancer activity of novel phenothiazines in glioblastoma
(University of the Western Cape, 2018)
Glioblastoma multiforme (GBM) remains the most malignant of all primary adult brain tumours. It is a highly invasive and vascularized neoplasm with limited treatment options and very low survival rate. GBM tumours are ...