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Content levels, in vitro dissolution and predicted bioavailability of flavonoids from Sutherlandia frutescens leaf powder and aqueous extracts
(University of the Western Cape, 2015)
Various formulations of the popular South African medicinal plant, Sutherlandia frutescens,are commercially available, with no documented specifications for quality assessment. With plans already underway for a clinical ...
Pharmacy perspectives in the design and implementation of a mobile cellular phone application as a communication aid for dispensing medicines to deaf people in the South African context
(University of the Western Cape, 2015)
South Africa's White Paper for the transformation of the health care system in South Africa (DOH, 2007) acknowledges major disparities and inequalities as a result of an imprint by apartheid policies. In its transition to ...
Cardiovascular effects of (13S)-9_, 13_- epoxylabda-6_(19), 15(14)diol dilactone, a diterpenoid isolated from the organic extract of leonotis leonurus leaves, in anaesthetized normotensive rats
(2009)
Plants used in traditional medicines have served as sources of some of the drug compounds used in medicines today, and could still serve as leads for then development of new drugs to treat existing chronic diseases such ...
Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive wistar rats
(University of the Western Cape, 2011)
Tulbaghia violacea Harv. (Alliaceae) is a small bulbous herb which belongs to the family, Alliaceae, most commonly associated with onions and garlic. In South Africa (SA), this herb has been traditionally used in the ...
Expanding presumptive male partner management of sexually transmitted infections (STIs) to Western Cape, South African community retail pharmacies
(University of the Western Cape, 2007)
The effect of industrialisation has thrust the pharmaceutical profession into a clinical paradigm where the approcah to pharmaceutical decisions is more disease and patient orientated. Consequently, South African community ...
An investigation into the medicinal properties of Tulbaghia alliacea phytotherapy
(University of the Western Cape, 2009)
The reproductive health of individuals is severely compromised by HIV infection, with candidiasis being the most prevalent oral complication in patients. Although not usually associated with severe morbidity, oropharyngeal ...
Population pharmacokinetics of terizidone and cycloserine in patients with drugresistant tuberculosis
(University of the Western Cape, 2019)
Introduction: Drug-resistant tuberculosis remains a major world health problem and
one of the leading cause of death worldwide. Despite adequate adherence to antituberculosis
drugs by patients, the emergence of drug-resistance ...
Polycyclic propargylamine derivatives as multifunctional neuroprotective agents
(University of the Western Cape, 2018)
The abnormal death of neurons in the central nervous system of individuals suffering from neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease and amyotrophic lateral sclerosis, ...
Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
(University of Western Cape, 2020)
Natural products have been an important source of drugs and novel lead compounds in drug
discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise
to medicinally relevant agents. ...
Novel norbornane derivatives as potential neuroprotective agents
(University of Western Cape, 2020)
Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological
functions as a result of gradual degeneration of neurons in the central nervous system. Even
though they are classified as ...