Browsing Faculty of Natural Science by Title
Now showing items 480-499 of 2563
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Design and evaluation of fast dispersible tablets of lamivudine using selected natural superdisintegrants
(University of the Western Cape, 2018)Fast dispersible tablets (FDTs) are solid single-unit dosage forms that are placed in the mouth and allowed to disperse or dissolve in the saliva without the need of water. The basic approach to formulating FDTs consists ... -
Design and implementation of a credible blockchain-based e-health records platform
(University of Western Cape, 2020)With the development of information and network technologies, Electronic Health Records (EHRs) management system has gained wide spread application in managing medical records. One of the major challenges of EHRs is the ... -
Design and Implementation of a Credible Blockchain-based E-health Records Platform
(University of the Western Cape, 2020)With the development of information and network technologies, Electronic Health Records (EHRs) management system has gained wide spread application in managing medical records. One of the major challenges of EHRs is the ... -
The design and simulation of a new experimental set up to measure nuclear level lifetimes
(University of the Western Cape, 2016)Measurements of nuclear level lifetimes are an important aspect of experimental nuclear physics. Such measurements determine transition matrix elements for nuclear structure research and also provide the widths of relevant ... -
Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
(University of Western Cape, 2020)Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. ... -
Design and synthesis of polycyclic amine derivatives for sigma receptor activity
(2013)New therapeutic strategies are needed for a diverse array of poorly understood neurological impairments. These include neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease, and the psychiatric ... -
Design of a helium-6 production target for the iThemba LABS Radioactive-ion Beam Facility
(University of the Western Cape, 2018)It is well known, that there is a severe lack of information available pertaining to neutron rich nuclei, specifically of those nuclei with mass numbers ≥ 60. These neutron rich nuclei are not easy to access in current ... -
Design of a thermoresponsive hydrogel for enhanced intratumoral permeation of a chemotherapeutic agent in oral squamous cell carcinoma
(University of the Western Cape, 2023)Introduction: Oral squamous cell carcinoma is the most common and aggressive cancer occurring in the oral cavity. Intravenous chemotherapy remains a pivotal part of treatment for the disease; however, these drugs cause ... -
The design of ultrasensitive immunosensors based on a new multi-signal amplification gold nanoparticles-dotted 4-nitrophenylazo functionalised graphene sensing platform for the determination of deoxynivalenol
(University of Western Cape, 2014)A highly dispersive gold nanoparticle-dotted 4-nitrophenylazo functionalised graphene nanocomposite (AuNp/G/PhNO2) was successfully synthesised and applied in enhancing sensing platform signals. Three label-free ... -
Design, analysis and simulation of a robust numerical method to solve Zika virus models
(University of the Western Cape, 2019)This thesis deals with the analysis and robust simulation of mathematical models describing Zika virus disease. Some background information about the occurrences of this disease and most recent literature indicating some ... -
Design, implementation and evaluation of a model for Service-learning in Pharmacy (SLIP) at a tertiary hospital
(University of the Western Cape, 2009)In recent years the focus of pharmacy practice has changed from being primarily 'drug-centred to' one which is 'patient-centred' (El-Awady et al., 2006, p. l ). Developments in pharmacy curricula worldwide are reflecting ... -
Design, implementation and evaluation of a model for service-learning in pharmacy (slip) at a Tertiary hospital
(2009)Background In recent years the focus of pharmacy practice has changed from being primarily ‘drugcentred to’ one which is ‘patient-centred’ (El-Awady et al., 2006, p.1). Developments in pharmacy curricula worldwide are ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
(University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by progressive memory loss and cognitive impairment. It is one of several neurodegenerative disorders occurring as a result of a process ... -
Designing next generation high energy density lithium-ion battery with manganese orthosilicate-capped alumina nanofilm
(University of the Western Cape, 2015)In the wide search for advanced materials for next generation lithium-ion batteries, lithium manganese orthosilicate, Li₂MnSiO₄ is increasingly gaining attention as a potential cathode material by virtue of its ability to ... -
Detecting Baryon Acoustic Oscillations with HI Intensity Mapping using MeerKAT
(University of the Western Cape, 2019)Future radio surveys as the Square Kilometer Array (SKA) and its precursor, the "Meer" Karoo Array Telescope (MeerKAT), will map the Neutral Hydrogen (HI) in large areas of the sky using the intensity mapping (IM). HI ... -
Detecting Galaxies in the Epoch of Reionization
(University of the Western Cape, 2017)The aim of this project was to develop a technique that allows us to measure the redshift of radio galaxies in the Epoch of Reionization. We achieved this by constructing a parameterization of the 21-cm absorption feature ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of the Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
The detection of meningococcal disease through identification of antimicrobial peptides using an in silico model creation
(University of the Western Cape, 2019)Neisseria meningitidis (the meningococcus), the causative agent of meningococcal disease (MD) was identified in 1887 and despite effective antibiotics and partially effective vaccines, Neisseria meningitidis (N. meningitidis) ...