Browsing Department of Medical BioSciences by Title
Now showing items 83-102 of 231
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The effects of maternal nicotine exposure during pregnancy or lactation on hypertension of the offspring
(University of the Western Cape, 2016)Blood pressure and heart rate is known to increase during smoking. These effects are specifically associated with nicotine while the other components of tobacco smoke seem to be of minor importance. It is becoming increasingly ... -
The effects of nanomaterials, in the presence and absence of serum proteins, on testicular cell metabolic processes and steroidogenesis
(University of the Western Cape, 2014)The aim of this study is to be the first to ascertain the effects of silver nanoparticles on testosterone production. The Ag NPs used for this study have the following characteristics; purity ≥ 99.5%; 66.7 % of particles ... -
The effects of PGA2 on cell cycle progression in oesophageal carcinoma cells
(University of the Western Cape, 2003)The molecular mechanisms causing anti-mitotic and cytotoxic effects of prostaglandin .A2 [PGA2 (CzoHroOa)] treatment of human oesophageal carcinoma (WHCO3) cells were investigated. WHCO3 cells, incubated with cytotoxic ... -
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
(University of Western Cape, 2021)Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled nanomaterials. These nanomaterials exhibit novel properties that are often very different to those of the bulk materials used ... -
The effects of titanium oxide nanoparticles on cultured cells and the immune system
(University of Western Cape, 2021)Engineered nanomaterials derived from various bulk materials are being developed in ever larger quantities and with very diverse chemical compositions. The physical and chemical properties of the smaller nanoparticles are ... -
The effects of various combinations of different Cdasses of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 and triple-negative MDA-MB 231 breast carcinoma cell lines
(University of the Western Cape, 2020)Globally, breast cancer is the most common cancer affecting women and it is predicted that in 2030 about 12 million deaths will occur with approximately 21.7 million new cases [2]. Genetic risk factors as well as race and ... -
The effects of various combinations of different classes of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 breast carcinoma cell line
(University of the Western Cape, 2014)This study investigated the effects of TKIs on the growth and proliferation of MCF-7 breast carcinoma cells in culture. MCF-7 cells were exposed to different concentrations of TKIs alone and in combination with each other. ... -
The efficiency of drinking water treatment plants in removing immunotoxins
(University of the Western Cape, 2010)The aim of this study was to evaluate the effectiveness of water treatment processes of two drinking water plants to remove immunotoxins and steroid hormones. Raw and treated drinking water was screened for effects on ... -
An electrophysiological exploration into the Sertoli cell, utilizing plant extracts with a view to contraception
(University of the western cape, 2003)Certa in medicinal plant extracts have been shown to have a contraceptive effect on male rats (Rajasekaran et al. , 1988) and mice (Kong et al., 1986). A possible site for the mechanism of action has been identified as the ... -
Epidemiological study of Tuberculosis in Macassar camp
(University of the Western Cape, 1995)The aim of this study was to determine and evaluate the prevalence of TB infection, active TB cases and the risk factors associated with TB infection in Macassar Camp in Macassar (about 40 km from Cape Town on the False ... -
Evaluating cape honey bee sperm quality and the in vitro effect of miticides on sperm functionality and structure
(University of Western Cape, 2021)Apis mellifera (honey bees) are essential pollinators and thus considered a keystone species. Reproductive success is therefore important to the survival of the species, with drone sperm quality playing a vital role in ... -
Evaluating the neuroprotective effects of fermented rooibos herbal tea in Wistar rats exposed to bisphenol-A during gestation and lactation
(University of the Western Cape, 2019)Exposure to endocrine-disrupting chemicals as bisphenol A (BPA) during gestation and early postnatal life is known to disrupt normal developmental processes and alter the body’s endocrine system leading to deleterious ... -
Evaluation of standard and development of new sperm function tests in selected primate species
(University of the Western Cape, 2017)Male infertility in humans has increased in the last few decades and could be as high as 40%, while up to 50% of these men have ''unexplained'' (idiopathic) infertility. Although newly developed molecular techniques have ... -
An evaluation of cancer biomarkers in normal ovarian epithelial cells and ovarian cancer cell lines
(University of the Western Cape, 2019)Introduction: Globally, there are over 190,000 new reported cases of ovarian cancers per annum. This comprises 3% to 4% of all cancers in women. Ovarian cancer is one of the leading causes of deaths in women. Ovarian cancer ... -
Evaluation of sperm functionality in non-human primates, focussing on sperm capacitation
(University of the Western Cape, 2019)The incidence of male infertility is increasing, with up to 50% of infertile males having “unexplained” (idiopathic) infertility. Newly developed molecular techniques have great value in detecting subtle causes of male ... -
An evaluation of the biopesticidal characteristics of Helichrysum marifolium and Helichrysum patulum and their effects on animal metabolism
(University of the Western Cape, 2002)There ate a number of pesticides that are suspected to be endocrine disrupters' Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, ... -
An evaluation of the biopesticidal characteristics of Helichrysum marifolium and Helichrysum patulum and their effects on animal metabolism
(University of the Western Cape, 2002)There are a number of pesticides that are suspected to be endocrine disrupters Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, ... -
An evaluation of the biopesticidal characteristics of Helichrysum marifolium and Hetichrysum patulum and their effects on animal metabolism
(University of the Western Cape, 2002)There ate a number of pesticides that are suspected to be endocrine disrupters' Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, ... -
An evaluation of the biopesticidal characteristics of Hetichrysum marifolium and Helichrysum patulum and their effects on animal metabolism
(University of the Western Cape, 2002)There ate a number of pesticides that are suspected to be endocrine disrupters' Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, ... -
Examination of the biocompatibility and anti-microbial activity of coated dental implants
(University of the Western Cape, 2017)Teeth are important to all people for chewing, speech and aesthetics. Tooth decay, periodontal disease and physical trauma or injuries are the main causes of tooth loss. There are different forms of treatment for tooth ...