Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 110-129 of 160
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Maternal nicotine expose during gestation and lactation induce premature aging of the lungs of the offspring
(University of the Western Cape, 2009)Tobacco smoking remains one of the leading causes of death worldwide. Despite all the efforts made by governments, researchers and communities to educate women about the dangerous effects of tobacco smoke and nicotine, ... -
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
(University of the Western Cape, 2018)Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties Over the years, microorganisms have become resistant to commonly used antimicrobial agents leading to multidrug resistance. ... -
Mercury leaching from dental amalgam fillings and its association with urinary zinc
(University of the Western Cape, 2019)Mercury (Hg) is an example of a toxic metal that is not essential for nutrition. It exists in organic and inorganic forms in seafood and vapour from dental amalgam fillings respectively. Elemental mercury (Hg0) from dental ... -
Microscopic analysis of In vitro and In vivo effects of functionalized gold nanoparticles on the liver, kidney, spleen, heart and pancreas of male wistar rats
(University of the Western Cape, 2022)Nanotechnology represents a promising knowledge based platform that can solve human needs and ailments, especially in cases like cancers, diabetes, antibiotic drug resistances etc. Many metallic nanoparticles are being ... -
The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro
(University of the Western Cape, 2014)Conjugated linoleic acids (CLA) are geometrical and positional isomers of n-6 octadecadenoic acid (linoleic acid, LA, 18:2n-6), which form part of a family of essential polyunsaturated fatty acids (PUFA). There are 28 ... -
The modulating effect of fatty acids on the lipid profile in colon epithelial mucosa in Vivo
(University of the Western Cape, 2009)Several abnormal conditions, including some cancers, have been associated with changes in the membrane lipid and FA composition. Dietary fat serves as a major source of lipids and FA, particularly the polyunsaturated fatty ... -
Molecular genetics: strategies to identify congenital cataract genes in captive-bred vervet monkeys
(University of the Western Cape, 2013)Molecular genetics: strategies to indentify congenital cataract genes in captive-bred Vervet monkeys Zandisiwe Emilia Magwebu MSc thesis, Department of Medical Biosciences, University of the Western Cape The present ... -
Molecular genetics: strategies to identify congenital cataract genes in captive-bred Vervet monkeys
(University of the Western Cape, 2012)The present study describes molecular aspects of inherited congenital cataract in captive-bred Vervet monkeys. Congenital cataracts are lens opacities that are present at birth or soon after birth and include hereditary ... -
Nanostructured immunosensor for low level detection of waterborne cryptosporidium
(University of the Western Cape, 2022)A major causative agent of gastrointestinal disease is Cryptosporidium, a protozoan waterborne parasite identified in over 70 countries. Cryptosporidium infection is a cause of high disease morbidity in children and the ... -
OnabotulinumtoxinA Injection for Glabellar Frown Lines as an Adjunctive Treatment for Depression
(University of the Western Cape, 2017)Depression is one of the most prevalent mental disorders worldwide. Sadness, fear and anger which are considered as negative emotions and are common in depression are coupled with the stimulation of the Corrugator supercilli ... -
Organisational commitment after a transformation process at a provincial government department
(University of the Western Cape, 2008)Organisations are by nature, dynamic entities that continuously undergo transformation in response to both internal and external pressures, which are imposed on them (Robbins, Odendaal & Roodt, 2003). Government departments ... -
Paediatric non-alcoholic fatty pancreas disease and aortic intimal medial thickness: A study identifying potential fatty infiltration of the pancreas and its association with aortic IMT in children exposed to teratogens during pregnancy
(University of the Western Cape, 2020)The incidence of non-communicable diseases is increasing worldwide, with South Africa being no exception. Non-communicable diseases are classified as non-infectious and are often referred to as lifestyle diseases as they ... -
The phenomenon of skin lightening among young adults, and the effect of selected plant extracts on tyrosinase and melanogenesis activity
(University of the Western Cape, 2023)Skin lightening practice refers to the use of skin lightening products to achieve a fairer skin complexion. This is common practice among people of several Asian, North American, South American countries. On the African ... -
The possible effect of Hypoxis hemerocalledia (African potato) on blood glucose levels : an in vitro study
(University of the Western Cape, 2015)The plant Hypoxis hemerocallidea, also known as the African potato, is commonly used as a traditional medicine to treat diabetes in South Africa. The mechanism by which it lowers blood glucose levels is not known. The ... -
Potamonautes spp. As a bioindicator for oestrogenic endocrine disrupting chemicals
(University of the Western Cape, 2017)Environmental pollutants, such as endocrine disrupting chemicals (EDCs), are a health concern as they can adversely affect animal health by interfering with the normal function of hormones. Oestrogenic EDCs can cause ... -
Potential neuroprotective effects of fermented rooibos herbal tea in a rat model of ischemic brain injury
(University of the Western Cape, 2015)Stroke is the third leading cause of death in South Africa, killing about 240 people a day and leaving survivors with residual disabilities. There is no clinically approved neuroprotective agent for stroke at the moment ... -
The potential neuroprotective effects of two South African plant extracts in hydrogen peroxide-induced neuronal toxicity
(University of the Western Cape, 2018)Background: Oxidative stress induced by reactive oxygen species has been strongly associated with many neurodegenerative diseases (NDDs) and many medicinal plant-derived products have been reported to exert potent antioxidant ... -
The potential therapeutic role of palm oil on prostate cancer
(University of the Western Cape, 2020)Prostate cancer is one of the heterogeneous groups of neoplastic diseases originating from the reproductive system of the male naming, the prostate gland. In the west, prostate cancer is the most common cancer affecting ... -
Prevalence and characterization of Gardnerella vaginalis in pregnant mothers with a history of preterm delivery
(University of the Western Cape, 2012)Risk factors such as intrauterine and vaginal infection put pregnant women at risk for delivering preterm. Bacterial vaginosis (BV) is a polymicrobial clinical syndrome commonly diagnosed in women of reproductive age, with ... -
The Prevalence of Members of the “Red Complex” in Pregnant Women as Revealed by PCR and BANA Hydrolysis.
(University of the Western Cape, 2005)Increased levels of oestrogen and progesterone during pregnancy may lead to periodontal disease. The anaerobic Gram-negative bacteria called red complex (Porphyromonas gingivalis, Tannerella forsythensis and Treponema ...