Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 21-40 of 160
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Cloning and expression of human cyclophilin A and its interaction with human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)Coronaviridae family is composed of a number of ribonucleic acid (RNA)-containing viruses currently classified into two genera, the coronavirus and torovirus. The family is classified together with the Arteviridae in the ... -
Cloning and expression of the M-gene from the human coronavirus NL-63 in different expression systems
(University of the Western Cape, 2008)Respiratory tract infections are one of the leading causes of morbidity and mortality across the world. This is especially true for infants, young children, the elderly and the immunocompromised. The strain placed on ... -
Cloning of Human Coronavirus NL-63 ORF3, M and E genes for antibody production
(University of the Western Cape, 2010)Human Coronavirus NL-63 is a respiratory virus with a high incidence rate, causing mild respiratory infections in children under the age of 18. The outbreak of Sever Acute Respiratory Syndrome (SARS) in 2003 sparked increased ... -
Comparative in vitro study of the anti-cancer effect of apricot and peach kernel extracts on human colon cancer cells
(University of the Western Cape, 2015)Amygdalin, a controversial anti-cancer agent, is a cyanogenic glycoside plant compound found in apricot and peach kernels. Both amygdalin and its patented form, Laetrile®, have been promoted and sold as "vitamin B-17", ... -
Comparison between chemical and tissue culture methods to monitor environmental estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
Comparison between chemical and tissue culture methods to monitor environmental Estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
A comparison of some aspects of the masticatory apparatus of the cape mole-rat, Georychus capensis with that of the cape dune molerat, Bathyergus suillus
(2009)Some African mole-rats of the family Bathyergidea have dramatically different ecological niches which may cause selective anatomical adaptations. Bathyergus suillus lives in sandy soil and eats a wide range of food whereas ... -
The development of a sars-cov-2 pseudoparticle assay for the detection of neutralizing antibodies in sera from covid-19 patients
(University of the Western Cape, 2024)The COVID-19 pandemic has caused devastating effects on the global socio-economic landscape. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19, and infections have led to ... -
Dexamethasone's impact on LPS-induced inflammation of blood-brain barrier endothelial cells
(University of the Western Cape, 2023)The blood-brain barrier (BBB) serves as a protective and regulatory barrier between the blood and the brain. Microvascular endothelial cells provide homeostatic regulation of the central nervous system (CNS). BBB integrity ... -
The distribution of the desert rain frog (breviceps macrops) in South Africa
(2009)The Distribution of the Desert Rain Frog (Breviceps macrops) in South Africa Kirsty Jane Bell M.Sc. Thesis, Department of Biodiversity and Conservation Biology, University of the Western Cape. The desert rain frog (Breviceps ... -
Do physiotherapy students employ evidence-based practice in the management of musculoskeletal disorders and sports injuries
(2013)Background: Musculoskeletal disorders (MSD’s) and sports injuries are commonly sustained throughout the world daily. They are dominant in many countries, with considerable cost involvement and impact on quality of life. ... -
Does maternal nicotine exposure during gestation and lactation change the oxidant-antioxidant status of the lungs of the offsprings and is tomato juice protecting the lungs of the offsprings?
(University of the Western Cape, 2009)Nicotine exposure to the fetus through tobacco smoking or nicotine replacement therapy during the whole period of gestation and lactation causes diverse effects on fetal and neonatal lung development, integrity and maturation ... -
Does Olea africana protect the heart against ischemiareperfusion injury?
(2009)Cardiovascular disease is a major health problem and remains the number one cause of death worldwide. For centuries, medicinal plants have been used in different cultures as medicines for the treatment and control of various ... -
Ecology and conservation of high altitude amphibians
(UWC, 2002)This study looked at the breeding ecology of the anurans, found in the Landdroskop mountain range in Grabouw, and some recommendations as to their conservation are made. There is very little known about the frogs in South ... -
Effect of basella alba and hibiscus macranthus on tm4 sertoli cell functions
(University of the Western Cape, 2009)Basella alba (BA) and Hibiscus macranthus (HM) are used by traditional healers in Cameroon to treat male sexual fertility problems. Previous studies showed that in vivo administration of the leaf extracts of both plants ... -
The effect of cissampelos capensis extract on prostate cancer, sertoli and leydig cell function
(University of the Western Cape, 2014)This study investigated the effect of the C. capensis extract (0.001, 0.01, 0.1, 1, 10, 100 1000 μg/ml) on LNCaP prostate cancer, TM3 Leydig and TM4 Sertoli cells for 24 and 96 hours. The following parameters were investigated: ... -
Effect of cissampelos capensis rhizome extract on human sperm capacitation and acrosome reaction
(2013)Cissampelos capensis, is commonly known by the Afrikaans name ‟dawidjies” or ‟dawidjieswortel”. C. capensis is the most important and best known medicinal plant of the family Menispermaceae used by the Khoisan and other ... -
The effect of doxorubicin encapsulated chitosan alginate nanoparticles and curcumin on multidrug resistant colon cancer cell lines
(University of the Western Cape, 2024)Purpose: Although chemotherapeutic drugs have improved the survival rate of patients diagnosed with colorectal cancer, resistance to chemotherapy frequently leads to therapeutic failure and poor patient outcomes. Multidrug ... -
Effect of Eurycoma longifolia (Tongkat Ali) on the prostate cancer cell line LNCaP
(2013)Eurycoma Longfolia Jack, also known as Tongkat Ali (TA) is a tropical plant belonging to the family of Simaroubaceae is widely distributed in South East Asian countries. The extracts of TA have been proven to have ... -
The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ...