Browsing Magister Pharmaceuticae - MPharm by Author "Mbamalu, Oluchi"
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Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
Tenghe, Lovette Asobo (University of the Western Cape, 2018)Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ... -
Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
Al-Derbali, Meftah Abdulhafied (University of the Western Cape, 2016)Background: Zidovudine (AZT) is a very useful drug for the management of Human Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ...