Browsing Magister Pharmaceuticae - MPharm by Issue Date
Now showing items 1-20 of 143
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Investigation of the mechanism of fenfluramine-induced pulmonary phospholipidosis in the rat lung model
(University of the Western Cape, 1993)The aim of this study was to investigate the mechanism of fenfluramine-induced pulmonary phospholipidosis, by comparing the profile and levels of induced phospholipids in the rat and the mode of phospholipase inactivation, ... -
The antimicrobial screening of four South African Asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotis auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
Effect of inhaled cationic poly-peptides on respiratory mechanics in the isolated perfused rat lung
(University of the Western Cape, 1998)The inhalation route is increasingly being considered as a viable option to deliver protein drugs into the body, but there has been few studies dealing with the safety of this strategy. The results of in vitro studies have ... -
The antimicrobial screening of four South African asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotts auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
An assessment of three Carpobrotus species extracts as potential antimicrobial agents.
(University of the Western Cape, 2001)For centuries, indigenous people in South Africa have used a variety of medicinal herbs to treat chronic infections. This investigation focused on three Carpobrotus species, in an attempt to assess their potential antimicrobial ... -
Formulation and evaluation of tablets manufactured from Dodonaea Angustifolia plant material
(University of the Western Cape, 2001)The liquid dosage form is the most frequently used form for traditional plant medicines. However, this dosage form is associated with many problems, e.g. physicochemical instability, microbial contamination, etc. which may ... -
Syndromic treatment of sexually transmitted infections: a western cape community pharmacist study
(University of the Western Cape, 2001)This cross-sectional survey of 85 randomly selected community pharmacists in the Western Cape, South Africa. estimates that 200 000 sexually transmitted infections (STl) cases are seen in private community pharmacies ... -
Pharmacological evaluation of the medicinal plants, pelargonium triste (l), elytropappus rhinocerotis (l.f), and olea europaea africana (mill.) for antidiarrhoeal activity in mice
(University of the Western Cape, 2001)Three medicinal plant species, Pelargonium triste (L.), Elytropappus rhinocerof,s (L.F.), and Olea europaea africana (Mill.), commonly used in the Western Cape traditional medicine to treat various ailments were assessed ... -
The chemical stability of betamethasone valerate and fluocinolone acetonide cream and ointment in cetomacrogol and emulsifying cream and ointment bases
(University of the Western Cape, 2002)The corticosteroids are powerful anti-inflammatory molecules but their usage is hampered by adverse effects. To minimise their adverse reactions, proprietary brands of topical corticosteroids are commonly diluted with a ... -
An Evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, Traditional Medicinal Plants used in the Western Cape
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifolia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
The influence of the proposed professional fee for community pharmacists on prescription income
(University of the Western Cape, 2002)prescription pricing in community pharmacies in South Africa involves a percentage mark-up on the cost of the product, followed by a varying discount to either the client or the medical scheme. The Pharmaceutical Society ... -
An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifulia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
Evaluation of satherlandia frutescens for anti.cancer activity
(University of the Western Cape, 2002)The claim for anti-cancer activity of the plant Sutherlandiafrutescens was investigated against some cancer cell lines in-vitro and against a dichlorvos induced chemical carcinogenesis in-vivo. A preliminary phytochemical ... -
Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart
(University of the Western Cape, 2004)This thesis discussed the cardiovascular effects of the aqueous leaf extract and a fraction of the methanol extract of Leonotis leonurus, a plant commonly used in traditional medicine in South Africa for the treatment of ... -
The development and evaluation of the Objective Structured Dispensing Examination (OSDE) for use in an undergraduate pharmacy training programme
(University of the Western Cape, 2004) -
The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material
(University of the Western Cape, 2004)Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing ... -
Neuropharmacological profile of Mentha longifolia: Effects on convulsion, nociception and pentobarbitone-induced sleep in mice
(University of the Western Cape, 2004)Mentha longifolia Huds., subspecies, capensis Briq, a plant species used for the treatment of epilepsy, painful conditions such as headache and toothache, and insomnia amongst other ailments, was investigated for anticonvulsant, ... -
Effects of the alkaloid present in the ethyl acetate: hexane (1 :4) fraction of Crinum macowanii on the isolated perfused rat heart
(University of the Western Cape, 2004)Crinum macowanii (CM) is used in traditional medicine in the treatment of various diseases including ischemic heart disease, rheumatic fever, cancer and skin diseases. The aqueous extract of CM bulbs was found have a ... -
The evaluation of markers for quality control studies of flavonoid-containing medicinal preparations
(University of the Western Cape, 2004)In spite of the high utilization of South African traditional medicine, the therapeutic potential and the chemical components of many plant preparations are unknown. For the safe and effective use of these medicinal ... -
Pharmacological evaluation of some central nervous system effects of Cotyledon Orbiculata
(University of the Western Cape, 2005)The use of traditional medicine through the use of medicinal plants in Africa and especially in South Africa has long been considered an important characteristic of people's daily lives and socio-cultural heritage. Cotyledon ...
