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The development and preparation of a quality control dossier for registration of Artemisia Afra capsules for the treatment of chronic Asthma by the South African health products regulatory authority
(University of the Western Cape, 2018)
The aim of this study was to determine quality control specifications needed for a dossier and an investigator's brochure of A. afra capsules, which can be used to motivate the registration and clinical testing of A. afra ...
Discovery of cytotoxic natural products from South African marine sponges
(University of the Western Cape, 2018)
Cancer is a major health problem worldwide and killing millions of people each year. The use
of natural products as chemotherapeutic agents is well established, however, many of the
currently available drugs are associated ...
Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
(University of the Western Cape, 2018)
Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ...
Design and evaluation of fast dispersible tablets of lamivudine using selected natural superdisintegrants
(University of the Western Cape, 2018)
Fast dispersible tablets (FDTs) are solid single-unit dosage forms that are placed in the mouth and allowed to disperse or dissolve in the saliva without the need of water. The basic approach to formulating FDTs consists ...
Antimicrobial discovery from South African marine algae
(University of the Western Cape., 2018)
Antimicrobials are chemical compounds that destroy or inhibit the growth of microorganisms.
The majority of these antimicrobials are actually natural products or natural product derived
with key examples being the pioneer ...