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Now showing items 11-20 of 22
Tungsten Telluride Quantum dot-based Biosensor for Alpha-Methylacyl CoA Racemase – An Emerging Prostate Cancer Biomarker
(University of the Western Cape, 2019)
Prostate cancer, commonly referred to as adenocarcinoma of the prostate, is the leading cause of cancer death in men in 46 countries, and it was estimated that by the end of 2018 there would approximately be 1.3 million ...
Genomic instability in South African breast cancer patients
(2013)
Breast cancer (BC) is one of the most common malignancies in women. Death results from treatment failure and metastatic disease. Thousands of lives might be saved if it was possible to detect and eliminate occult metastatic ...
Electrochemical Aptasensing of B-Type Natriuretic Peptide-A Biomarker for Myocardial Infarction
(University of the Western Cape, 2019)
infarction (MI) affects many parts of the western world and in South Africa alone it is estimated that MI is responsible for 1 in 6 deaths (17.3%). Traditional diagnostic methods for MI include an electrocardiograms and ...
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects.
(University of the Western Cape, 2020)
Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ...
Genetic variation between two subspecies of Reedfrogs in the genus Hyperolius (Anura: Hyperoliidae)
(University of the Western Cape, 1993)
The frog genus Hyperolius is the largest of 19 genera in the Hyperoliidae (Channing, 1939). The members of the genus display considerable morphological homogeneity with a diversity of dorsal colour patterns. The genus is ...
Aberrations in the Retinoblastoma susceptibility gene in tumours from South Africa oesophageal cancer patients
(University of the Western Cape, 1996)
Little is known about the genetic events occurring in oesophageal cancer and very few studies have been undertaken to analyse oesophageal tumours from South African patients in this regard. Inactivation of numerous tumour ...
Bioactivity guided fractionation of Sutherlandia frutescens extracts for the induction of apoptosis
(University of the Western Cape, 2003)
Sutherlandia frutescens popularly known as "cancer bush" or "kankerbos" is indigenous to South Africa and claimed by traditional healers to have wide therapeutic potential, most specifically against cancer. To verify these ...
Identification and partial characterisation of a putative novel plant stress response gene from Arabidopsis thaliana.
(University of the Western Cape, 2000)
Exposure of plants to stress results in the expression of plant genes whose products play a role in defence responses against the stress. Stress stimuli to which plants may be exposed are wounding, drought, salinity, ...
"Genetic variation between two subspecies of reedfrogs in the genus Hyperolius (Anura: Hyperoliidae)"
(University of the Western Cape, 1993)
H. m. broadleyi and H. m. verrucosus are not only different in terms of colour pattern, but distinct genetic differences were detected in restriction site maps of their ribosomal DNA. A sequence divergence value of 13,8% ...
Genetic variation of rana fuscigula in Southern Africa
(University of the Western Cape, 1994)
Naturalists have long been engaged in describing and explaining diversity in the biological world. The discovery of the molecular basis of inheritance has led to rapid increase in the use of biological macromolecules in ...