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Market segmentation and factors affecting stock returns on the JSE
(2008)
This study examines the relationship between stock returns and market segmentation. Monthly returns of stocks listed on the JSE from 1997-2007 are analysed using mostly the analytic factor and cluster analysis techniques. ...
Characterising the Prevalence and Mode of CXCR4 Usage in HIV-1 Group M Subtype C
(University of the Western Cape, 2013)
Determination of CXCR4-usage patterns is essential in establishing suitability
of CCR5 antagonist prescription in HIV-1 infected individuals to
prevent treatment failure. Previous studies have suggested a switch ...
Effects of nucleotide variation on the structure and function of human arylamine n-acetyltransferase 1
(2012)
The human arylamine N-acetyltransferase 1 (NAT1) is critical in determining the duration of action and pharmacokinetics of amine-containing drugs such as para-aminosalicylic acid and para-aminobenzoyl glutamate used in ...
An evolutionary genomics approach towards analysis of genes implicated in transmission of trypanosomes between tsetse fly and mammalian host
(2009)
Human African trypanosomiasis is the world’s third most important parasitic disease affecting human health after malaria and schistosomiaisis. The world health organization estimates approximately 60 million people at risk ...
A comparative genomics approach towards classifying immunity-related proteins in the tsetse fly
(2009)
Tsetse flies (Glossina spp) are vectors of African trypanosome (Trypanosoma spp)
parasites, causative agents of Human African trypanosomiasis (sleeping sickness) and Nagana in livestock. Research suggests that tsetse fly ...
Assessment of genome visualization tools relevant to HIV genome research: development of a genome browser prototype
(University of the Western Cape, 2004)
Over the past two decades of HIV research, effective vaccine candidates have been elusive. Traditionally viral research has been characterized by a gene -by-gene approach, but in the light of the availability of complete ...
HIV subtype C diversity: analysis of the relationship of sequence diversity to proposed epitope locations
(University of the Western Cape, 2002)
Southern Africa is facing one of the most serious HIV epidemics. This project contributes to the HIVNET, Network for Prevention Trials cohort for vaccine development. HIVÂ’s biology and rapid mutation rate have made vaccine ...
Incidence and regulatory implications of single Nucleotide polymorphisms among established ovarian cancer genes
(University of the Western Cape, 2009)
OVARIAN cancer research focuses on answering important questions related to the disease, determining whether new approaches are feasible to contribute towards improving current treatments or discovering new ones. This study ...
miRNAMatcher: High throughput miRNA discovery using regular expressions obtained via a genetic algorithm
(University of the Western Cape, 2008)
In summary there currently exist techniques to discover miRNA however both require many calculations to be performed during the identification limiting their use at a genomic level. Machine learning techniques are currently ...
The development of a single nucleotide polymorphism database for forensic identification of specified physical traits
(University of the Western Cape, 2009)
Many Single Nucleotide Polymorphisms (SNPs) found in coding or regulatory regions within the human genome lead to phenotypic differences that make prediction of physical appearance, based on genetic analysis, potentially ...