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Now showing items 41-50 of 73
Pharmacological evaluation of antidiarrhoeal and antidiabetic activities of Syzygium Cordatum Hochst. ex C. Krauss
(University of the Western Cape, 2011)
Syzygium cordatum is a medicinal plant indigenous to South Africa and Mozambique, commonly used to treat stomach aches, diabetes, respiratory problems and tuberculosis. In spite of the folklore use, adequate scientific ...
Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)
Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by
progressive memory loss and cognitive impairment. It is one of several
neurodegenerative disorders occurring as a result of a process ...
Polycyclic compounds as carriers for neuroactive non- steroidal anti-inflammatory drugs
(University of the Western Cape, 2017)
Recent scientific findings have highlighted the beneficial roles of polycyclic cage compounds in neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Further interest into the chemistry of these compounds ...
The development and preparation of a quality control dossier for registration of Artemisia Afra capsules for the treatment of chronic Asthma by the South African health products regulatory authority
(University of the Western Cape, 2018)
The aim of this study was to determine quality control specifications needed for a dossier and an investigator's brochure of A. afra capsules, which can be used to motivate the registration and clinical testing of A. afra ...
Analysis on access to antiretroviral therapy for patients with different income and educational level, and the effect of treatment on quality of life after two to three months of therapy
(University of the Western cape, 2017)
Access to antiretroviral therapy (ART) for HIV positive patients has brought
hope and a chance to a healthier longer life with improved quality of life (QoL). In this study we
explored the difference in health related ...
Discovery of cytotoxic natural products from South African marine sponges
(University of the Western Cape, 2018)
Cancer is a major health problem worldwide and killing millions of people each year. The use
of natural products as chemotherapeutic agents is well established, however, many of the
currently available drugs are associated ...
Polymer Coating of an Optimized Nano Lipid Carrier System of Harpagophytum Procumbens Extract for Oral Delivery
(University of the Western Cape, 2017)
Harpagophytum procumbens is a traditional medicinal plant widely used in South African
traditional healthcare to treat a range of ailments like degenerative rheumatoid arthritis,
osteoarthritis, tendonitis, kidney inflammation, ...
Evaluation of the anticonvulsant activity of Elytropappus rhinocerotis (L.f) Less
(University of the Western Cape, 2016)
M.Pharm thesis, Discipline of Pharmacology, School of Pharmacy, University of the Western
Cape. Epilepsy is a worldwide neurological disorder which is also prevalent in South Africa. Herbal
medicines, besides orthodox ...
Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
(University of the Western Cape, 2018)
Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ...
Design and evaluation of fast dispersible tablets of lamivudine using selected natural superdisintegrants
(University of the Western Cape, 2018)
Fast dispersible tablets (FDTs) are solid single-unit dosage forms that are placed in the mouth and allowed to disperse or dissolve in the saliva without the need of water. The basic approach to formulating FDTs consists ...