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Now showing items 21-30 of 47
Selection, synthesis and evaluation of novel drug-like compounds from a library of virtual compounds designed from natural products with antiplasmodial activities
(University of the Western Cape, 2020)
Malaria is an infectious disease which continues to kill more than one million people every year and the African continent accounts for most of the malaria death worldwide. New classes of medicine to combat malaria are ...
Change Management in a biopharmaceutical company
(University of Western Cape, 2020)
This study aimed to review the change management implemented in a Biopharmaceutical company in Cape Town in the light of existing literature on change management theory. Three main constructs were identified: process of ...
The formulation and characterisation of corticosteroid loaded Ethosomes for topical delivery
(University of the Western Cape, 2020)
Background/Introduction: Atopic dermatitis (AD) is one of the most prevalent diseases worldwide. It is a rapidly growing field of study with several research avenues to explore its pathophysiology and to find innovative ...
The impact of Niacin on PCSK9 levels in vervet monkeys (Chlorocebus aethiops)
(University of Western Cape, 2020)
Cardiovascular diseases (CVDs) such as ischaemic heart diseases, heart failure and stroke
remain a major cause of death globally. Various deep-rooted factors influence CVD
development; these include but are not limited ...
The impact of Niacin on PCSK9 levels in vervet monkeys (Chlorocebus aethiops)
(University of the Western Cape, 2020)
Cardiovascular diseases (CVDs) such as ischaemic heart diseases, heart failure and stroke remain a major cause of death globally. Various deep-rooted factors influence CVD development; these include but are not limited to ...
Chalcone and curcumin hybrids of indole propargylamines as multifunctional neuroprotective agents
(University of the Western Cape, 2020)
Neurodegenerative disorders (NDs) are a range of chronic brain disorders that includes
amongst others motor function loss. Parkinson’s disease (PD) is one of the common NDs that
has an insidious onset and diagnosed when ...
Transparency in medicines registration decision making: A closer look at National Medicines Regulatory Authorities (NMRAs) within the Southern African Development Community (SADC) region.
(University of the Western Cape, 2020)
Medicines registration decision-making and regulatory best practice involve transparent and consistent rule making and processes with publicly available published assessment decisions and reports (Kaine, 2020). Publication ...
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)
Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ...
Adverse Foetal Outcomes in Gestational Diabetes: A Systematic Review and Meta-analysis
(University of the Western Cape, 2020)
Gestational diabetes mellitus (GDM) is a condition that affects pregnant women and is one of the most common complications related to pregnancy. According to the World health organisation (WHO), the usual window for ...
The impact of universal health coverage and national health expenditure on the main health determinants on central America countries and the Caribbean
(University of Western Cape, 2020)
Health is considered as a sensitive marker of the sustainable development of a population. In Central America and Caribbean (CAC) region, the majority of countries are considered middle-income economies with significant ...