Browsing Faculty of Natural Science by Author "Pool, Edmund J."
Now showing items 1-20 of 21
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Assessment of raw and treated sewage using in vitro assays
Booysen, Robin Alvin (University of the Western Cape, 2014)Water scarcity is becoming an increasingly relevant problem for urban centres, especially in Southern Africa. However, water availability is not the only concern for consumers, because water quality is just as relevant. ... -
Assessment of the biological quality of raw and treated effluents from three sewage treatment plants in the Western Cape, South Africa
Hendricks, Rahzia (University of the Western Cape, 2011)The aim of this study was to compare the water quality of raw wastewater and treated sewage effluents from three different sewage treatment plants in the Western Cape, South Africa. The treatment plants investigated are ... -
Cell culture biomarkers for monitoring of wastewater pollutants
Makene, Vedastus Wilfred (University of the Western Cape, 2021)Wastewater is normally composed of a mixture of pollutants. The type and composition of pollutants in a particular wastewater depend on the source of origin. The source and characteristics of a particular wastewater determine ... -
Comparison between chemical and tissue culture methods to monitor environmental estrogens
Baguma, Richard (University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
The development and implementation of biomarker assays for estrogenic endocrine disruptors
Swart, Johannes Cornelius (University of the Western Cape, 2008)Endocrine disrupting chemicals (EDCs) are compounds found in the environment that have the potential to disrupt normal endocrine function. Estrogenic EDCs (e-EDCs) is a subclass of EDCs and is defined as substances ... -
The effects of artificial and natural sweeteners on various physiological systems
Rahiman, Farzana (University of the Western Cape, 2011)This study aimed to investigate the effects of commercially available natural (sugar cane molasses, white sugar and brown sugar) and artificial (Canderel, Equal, Natreen, Sweetex, Splenda and Swheet) sweeteners on various ... -
Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
Abuaniza, Zaroug A.M. (University of the Western Cape, 2013)Modulation of the male reproductive system occurs as a result of exposure to endocrine disrupting compounds (EDCs) in different life stages. The effects of EDCs on the male reproductive system include infertility, decreased ... -
The effects of nanomaterials, in the presence and absence of serum proteins, on testicular cell metabolic processes and steroidogenesis
Muller, Ashley George (University of the Western Cape, 2014)The aim of this study is to be the first to ascertain the effects of silver nanoparticles on testosterone production. The Ag NPs used for this study have the following characteristics; purity ≥ 99.5%; 66.7 % of particles ... -
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
Volkmann, Tina (University of Western Cape, 2021)Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled nanomaterials. These nanomaterials exhibit novel properties that are often very different to those of the bulk materials used ... -
The efficiency of drinking water treatment plants in removing immunotoxins
Malan, Cheryl (University of the Western Cape, 2010)The aim of this study was to evaluate the effectiveness of water treatment processes of two drinking water plants to remove immunotoxins and steroid hormones. Raw and treated drinking water was screened for effects on ... -
The immune-modulating activity of Artemisia afra
Kriel, Yusra (University of the Western Cape, 2010)This study shows that herbs can be effectively screened for potiential bio-activity using in vitro methods. Further studies will be needed to better explore Artemisia afra’s effect on immunoregulation, particularly ... -
The immune-modulating activity of Sutherlandia frutescens
Kisten, Najwa (University of the Western Cape, 2010)The aim of this study was to investigate the effects of Sutherlandia frutescens on the inflammatory response and T cell differentiation in vitro using cytokines as biomarkers. Whole blood cells containing various concentrations ... -
An in vitro study on the immunotoxicity of sewage effluents discharged into the Eerste River-Kuils river water catchment system
Magcwebeba, Tandeka (2008)"The aim of the study was to use in vitro human whole blood cultures to screen the water samples collected from the Eerste/Plankenbrug river system for cytotoxicity and inflammatory activity and for the first time investigate ... -
An in vitro study on the immunotoxicity of South African beer
Neethling, Michelle (University of the Western Cape, 2008)Traditionally brewed beers are of cultural and economic importance to many African nations. The presence of mycotoxins in African beer is a topic that needs to be addressed, since most African countries have a climate of ... -
Potamanautes warreni biomarker assays to monitor silver nanomaterial contaminants in aquatic environments
Walters, Chavon Rene (University of the Western Cape, 2016)There has been extensive growth in nanoscale technology in the last few decades to such a degree that nanomaterials (NMs) have become a constituent in a wide range of manufactured commercial and domestic products. This ... -
Potamonautes spp. As a bioindicator for oestrogenic endocrine disrupting chemicals
Schoeman, Dewald (University of the Western Cape, 2017)Environmental pollutants, such as endocrine disrupting chemicals (EDCs), are a health concern as they can adversely affect animal health by interfering with the normal function of hormones. Oestrogenic EDCs can cause ... -
The screening of phyto-pesticides for potential adverse effects on human health
Shoko, Yeukai Phoebe (University of the Western Cape, 2010)Pesticides are designed to control or eliminate pests such as insects, rodents, weeds, bacteria, and fungi. They are used at a global scale for agricultural produce. Although pesticides play a significant role in increasing ... -
The assessment of Namibian water resources for endocrine disruptors
Faul, Andre Karel (University of the Western Cape, 2018)Namibia is the driest sub-Saharan country in Africa and it is characterised by low and variable rainfall. As a result, potable water in this mostly semi-arid country is considered an extremely valuable resource. Given ... -
The use of in vitro assays to screen for endocrine modulation
Hendricks, Rahzia (University of the Western Cape, 2008)Aspalathus linearis (A. linearis), commonly known as Rooibos tea or Red bush tea and Camellia sinensis (C. sinensis) or Black tea are beverages that are consumed throughout the world. These teas possess antioxidant, ... -
The use of whole blood cell cultures as a model for assessing the effects of Septilin on the immune system
Hoosen, Mujeeb (University of the Western Cape, 2017)In the past three decades there has been a huge increase in the use of herbal medicine globally. The active principles of these herbal medicines are mostly unknown with supportive evidence for safety and efficacy very ...